Functional Genomics and Its Implications for Molecular Medicine
2006
Technological development in genetics and genomics provides unprecedented possibilities to identify the underlying molecular basis of many common diseases. With the availability of the human genome sequence and growing information on the most frequent DNA variations combined with the molecular analysis on the RNA expression and protein level, diseases might be characterized in the future at the molecular level. Describing gene function and the specific role of DNA, RNA, and proteins in the disease process provides novel diagnostic tools and treatment. Ultimately, the goal is to provide optimal therapy for each patient. Understanding how the unique genetic signature of an individual influences the risk and prognosis of disease will be the basis for individualized medicine in the years to come.
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