Immunothérapie adoptive par macrophages activés dans les cancers colorectaux métastatiques

Abstract Cytotoxic macrophages (MAK) have been obtained by blood cytapheresis, elutriation of monocytes, culture and activation. Six patients with resistant metastatic colorectal cancer have been treated with MAK. Two stabilizations and some biological evidence of activity were observed. MAK therapy requires further evaluation.