Novel indoletriazole alkaloid as well as preparation method and antifungal application thereof

2011 
The invention relates to the technical field of medicines and discloses an indoletriazole alkaloid antifungal compound with a novel framework, i.e. fructus evodiae triazole alkali (3-[2-N-methyianiline]-triazolo[4,3-a]-3,4-dihydto-beta-carboline) which is a compound with a brand-new framework. The structural formula is shown at right. The invention also relates to a preparation method and application of the indoletriazole alkaloid antifungal in the field of medicines. Particularly, the compound has strong antifungal activity, and compared with the antifungal medicaments clinically applied at present, the compound has the advantages of high efficiency, low toxicity, broad antifungal spectrum, and the like, opens a new approach for deeply researching and developing new antifungal medicaments and can be used for preparing new antifungal medicaments.
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