Eszopiclone prevents excitotoxicity and neurodegeneration in the hippocampus induced by experimental apnea.

Simon J. Fung,Ming-Chu Xi,Jian-Hua Zhang,Jack Yamuy,Sharon Sampogna,Kevin L. Tsai,Vincent Lim,Francisco R. Morales,Michael H. Chase

Eszopiclone prevents excitotoxicity and neurodegeneration in the hippocampus induced by experimental apnea.

2009

Simon J. Fung
Ming-Chu Xi
Jian-Hua Zhang
Jack Yamuy
Sharon Sampogna
Kevin L. Tsai
Vincent Lim
Francisco R. Morales
Michael H. Chase

Study Objective: This study was designed to determine the effects of eszopiclone on apnea-induced excitotoxic synaptic processes and apoptosis in the hippocampus.

Keywords:

Eszopiclone
Anesthesia
Psychology
Neurodegeneration
Agonist
Hypnotic
Neuroscience
Central nervous system
Hippocampus
Excitatory postsynaptic potential
Excitotoxicity

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