Prevention of post procedural acute kidney injury in the catheterization laboratory in a real-world population

Abstract Background Radiologists and cardiologists have a remarkably different approach to the clinical importance and to the need for prophylactic treatment of contrast-induced acute kidney injury (CI-AKI). Objectives To evaluate the efficacy of forced diuresis with matched controlled hydration (FMH) in a real-world, high risk population. Methods This is an investigator-driven, single-center, retrospective analysis of prospectively collected data. A total of 150 consecutive patients undergoing coronary angiography, angioplasty or TAVR who were treated with FMH were compared to a matched historical control cohort. Results In the FMH treated patients, eGFR improved following the procedure from 37ml/min per 1.73m 2 at baseline to 39ml/min per 1.73m 2 ( p p 2 to 33.2ml/min per 1.73m 2 post procedurally ( p p p Conclusions In patients undergoing coronary angiography, angioplasty or TAVR, who are considered high risk to develop post procedural AKI, forced diuresis with matched controlled hydration resulted in a significant net creatinine decrease, eGFR increase and a decrease in the incidence of AKI.