DNA MICROARRAY ANALYSIS OF TRANSCRIPTIONAL RESPONSES OF YEAST CELLS TO EXPRESSION OF CORE PROTEIN OF HEPATITIS C VIRUS

We monitored transcriptional changes in yeast cells in response to induced expression of the core protein of hepatitis C virus (HCV) using a DNA microarray. Expression of 16 genes involved in the unfolded-protein response was enhanced by inducing expression of the core protein in yeast cells.