SIMULATION ANALYSIS OF DEFORMATION AND STRESS OF TRACHEAL AND MAIN BROCHIAL WALL FOR SUBJECTS WITH LEFT PULMONARY ARTERY SLING

Left pulmonary artery sling (LPAS) is a kind of severe congenital anomaly, where the stenoses usually occur at trachea and main bronchi for the external compression of the artery sling. Computed tomography (CT) images can provide accurate morphological analysis, but the airflow and its effects on the airway wall are unknown and seldom investigated. In the present study, a uni-directional coupling fluid–structure interaction (UCFSI) method is employed to simulate the deformation and stress of tracheal and main bronchial wall for four LPAS subjects and one health control. Much higher airflow velocity is observed for LPAS subjects due to the stenosis, and the deformation and equivalent stress of airway wall are about 50–900 and 90–1000 times of the health control, respectively. The direction of tracheal shift may be related to the airway shape, and is opposite to the net reaction force. The influences of inlet flow velocity and wall thickness on the deformation and stress are significant and their relationsh...