Prolonged survival after radiofrequency ablation of synchronous colorectal liver metastases

3763 Background: Synchronous liver metastasis (SLM), commonly defined as liver metastasis occurring within 12 months of the colon primary, represents 13–25% of the 90,000 newly diagnosed colorectal liver metastases. SLM have historically been found to have a worse overall survival when compared to metachronous lesions. The primary reason for this worse overall survival has been related to a majority of patients having unresectable disease because of multiple bilobar tumors or comorbid conditions. We hypothesized that patients with synchronous liver metastases would benefit from an aggressive ablation and resection to the same degree as patients with metachronous metastases. Methods: Review of our prospective database revealed 64 pts with unresectable colorectal liver metastases treated since 1998. The vast majority of patients underwent RFA as an open procedure. Survival was determined by the Kaplan-Meier. Results: Sixty-four pts underwent treatment for 200 liver metastases (38 resected, 162 RFA; mean 3.1...