Abstract 14101: CES1 Deficiency is Associated With Oxidative Stress and Endoplasmic Reticulum/Mitochondrial Injury in Pulmonary Endothelial Cells

Stuti Agarwal,Ananya Chakraborty,David Condon,Elya A. Shamskhou,Hiral V Patel,Lichao Liu,James West,Karthik Suresh,Bruce D. Hammock,Marlene Rabinovitch,Joseph C. Wu,Mark R. Nicolls,Vinicio A Dejesus Perez

Abstract 14101: CES1 Deficiency is Associated With Oxidative Stress and Endoplasmic Reticulum/Mitochondrial Injury in Pulmonary Endothelial Cells

2021

Stuti Agarwal
Ananya Chakraborty
David Condon
Elya A. Shamskhou
Hiral V Patel
Lichao Liu
James West
Karthik Suresh
Bruce D. Hammock
Marlene Rabinovitch
Joseph C. Wu
Mark R. Nicolls
Vinicio A Dejesus Perez

Background: Pulmonary Arterial Hypertension (PAH) is a life-threatening disease characterized by loss of pulmonary microvessels and vascular remodeling. BMPR2 insufficiency in PAH is associated wit...

Keywords:

Pathology
BMPR2
Disease
Ventricular remodeling
Pulmonary hypertension
Medicine
Oxidative stress
Endoplasmic reticulum
Vascular disease

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