A Study on Thermal Response of Nanoparticles in External Magnetic Field

Hyperthermia has become an important area of research for cancer treatment throughout the world. Choosing appropriate magnetic nanoparticles for specific performance at the cancerous site of the body is a major problem. In this research work, iron oxide nanoparticles were synthesized using laser ablation and Ag@α‑Fe2O3 and γ-Fe2O3 nanoparticles using chemical methods. The size and shape of synthesized nanoparticles were characterized by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). These nanoparticles were then exposed to the alternating magnetic field in a fluid medium in a calorimeter. The heat generated by nanoparticles in the response to the applied magnetic field due through Neel relaxation and through Brown relaxation effects was measured using an array of the k-type thermometer. Their thermal responses in AC magnetic field to time regarding their types were studied. γ-Fe2O3 produced more heat, sufficient enough to kill the cancer cells selectively.