[Clinical evaluation study on long-term effect of acupuncture with pattern/syndrome differentiation on functional dyspepsia].

Objective To compare the efficacy difference in the treatment of functional dyspepsia between acupuncture at the acupoints selected by pattern/syndrome differentiation and domperidone.Methods Seventy cases were randomized into an acupuncture group(35cases)and a western medication group(35cases).In the acupuncture group,Zusanli(ST 36)and Neiguan(PC 6)were selected.Taichong(LR 3)and Neiting(ST 44)were added for excess syndrome while Gongsun(SP 4)and Yinlingquan(SP 9)were added for deficiency syndrome.A pair of electrodes was attached to one acupoint and an assistant point(2mm next to the acupoint centripetally)and stimulated with disperse-dense wave at 2Hz/100Hz,once a day.In the western medication group,domperidone was prescribed for oral administration,10mg each time,three times a day.In the two groups,the treatment of 5days made one session and 4sessions were required totally.Nepean dyspepsia index(NDI)was compared after treatment,1,2,3,4and 5months after treatment between the two groups respectively.Results The score of symptom and score of life quality in NDI after treatment and at each follow-up time point were improved obviously in the acupuncture group as compared with those before treatment(all P0.01).In the western mediation group, the score of symptom and the score of life quality in NDI after treatment and in follow-up of 1,2and 3months were improved obviously as compared with those before treatment(all P0.01),but the differences were not significant in follow-up of 4and 5months(both P0.05).Compared with the western medication group,the symptom score of NDI was reduced obviously after treatment and in each time point of follow-up in the acupuncture group(P0.05,P0.01),and the score of life quality was increased obviously(P0.05,P0.01).Conclusion Acupuncture at the acupoints selected by pattern/syndrome differentiation and domperidone are effective in the treatment of functional dyspepsia.Domperidone is unsatisfactory in the long-term effect,but acupuncture achieves the positive short-term and long-term effects on functional dyspepsia.