Bromsulfalein Retention Due to Administration of a Gall-Bladder Dye (Bunamiodyl)

IT has been observed that in the study of patients hospitalized for investigation of liver or gall-bladder disease, or both, studies of bromsulfalein excretion and cholecystography are often done concomitantly. In the usual manner this implies the administration of an iodine dye for the cholecystogram on the night before x-ray studies and the addition of a bromine-containing compound (bromsulfalein) on the next morning. On a number of occasions we have noted that the bromsulfalein retention measured in this fashion is frequently out of proportion to existing liver disease, and with repeated determinations at a later date, the values have shown . . .