Use of House Mice in Biomedical Research

What was true in 1981 is even more true today. The number of laboratory mice used as a model for human and animal biomedical research continues to grow at a rapid rate. The mouse's usefulness as a biomedical model has been sharply enhanced by recent advances in the ability to experimentally modify its genome. In this issue oilLAR Journal, a group of experts focus on the role of the mouse in biobehavioral research. Our goal is to review selected parts of the literature on laboratory mouse behavior and to assess behavioral measurement procedures that may be useful to investigators utilizing this common biomedical model. The word mouse in the English language can be traced