Analysis on the infection of 109 close contacts with COVID-19

Objective: To investigate the infection of novel coronavirus in close contacts with COVID-19 patients, and to analyze the risk factors and the effectiveness of intervention measures Methods: The close contacts were investigated by questionnaire, and infection of novel coronavirus was counted after 14 days of observation Chi-square inspection and multivariate Logistic regression analysis was used to study the correlation between some factors and infection, such as age, weight, basic diseases, smoking, drinking, et al The influence of wearing masks, washing hands, and preventive drugs on the prognosis of close contacts was analyzed Results: A total of 109 close contacts were investigated, and 20 cases were diagnosed as COVID-19 The age of the infected group was significantly higher than that of the non-infected group (66 0±14 8 vs 44 3±21 3, P< 0 01) Old age, hypertension, and insomnia were high risk factors for infection of novel coronavirus Frequent hand- washing could significantly reduce the risk of novel coronavirus infection Preventive use of antiviral drugs and traditional Chinese medicine could not reduce the risk of novel coronavirus infection The use of antibiotics couldn't reduce the risk of new coronavirus infection in close contacts Conclusion: Elderly people, especially those with hypertension, have a high risk of new coronavirus infection Frequent hand washing and good sleep could effectively reduce the risk of new coronavirus infection © 2021, Editorial Board of Medical Journal of Wuhan University All right reserved