Clinical Features of Stomach Cancer with Metastasis to the Urinary Bladder

Background/Aims: Metastatic urinary bladder cancer from a distant organ is unusual. The aim of this study was to analyze clinical characteristics of bladder metastases from stomach cancer. Methods: We reviewed the medical records of 14 patients with metastatic bladder cancer from stomach cancer who admitted at Asan Medical Center between June 1989 and April 200 1. Results: The mean age was 47.8 (31-61) years. Nine patients were male and 5 patients female. Mean duration between diagnosis of metastatic bladder cancer and the onset of stomach cancer was 19.7 months (0-40). The most common symptom was hematuria (9 cases), followed by dysuria, frequency, and flank pain. Patients underwent CT scan, urine cytology, IVP, and cystoscopy to evaluate metastasis of the urinary bladder. The locations of metastatic urinary bladder cancer were lateral wall (n=4), dome (n=3), posterior wall (n=3), trigone and dome (n=1), uretero-vesical junction (n=1), and entire bladder (n=2). Three patients underwent transurethral resection and one patient took radical cystectomy. Mean survival duration was 5 months (2-11 months). Conclusions: When urologic symptoms newly develop in patients with stomach cancer, metastasis to the urogenital organs should be considered.