Pharmacokinetics of Ropivacaine in Patients with Chronic End-stage Liver Disease
2007
Background:Ropivacaine is mainly eliminated by hepatic metabolism. The authors studied the effect of chronic end-stage liver disease on the pharmacokinetics of ropivacaine.Methods:Thirteen patients with chronic end-stage liver disease and eight healthy volunteers received a single dose of 0.6 mg/kg
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