COST-EFFECTIVENESS ANALYSIS PENGOBATAN DEMAM TIFOID ANAK MENGGUNAKAN SEFOTAKSIM DAN KLORAMFENIKOL DI RSUD. PROF.DR. MARGONO SOEKARJO PURWOKERTO

Typhoid fever is an endemic disease in developing country. The highest incidency of typhoid fever is in children. There are many antibiotics are used to medicate Thyphoid fever in children. The using of different antibiotics affects higher medicine cost that patients have to pay. Therefore the research is needed for knowing the cost effective of the two antibiotics between the use of cefotaxime and chloramphenicolin medication of thyphoid fever in children in RSUD Prof.Dr. Margono Soekarjo is needed. This research used non experimental analitic method with cross -sectional study. This study included 26 typhoid fever children who were treated in first class of Aster room in RSUD Prof. Dr. Margono Soekarjo.It used secondary datas which included medicine costs (drugs, laboratories dan room) and day of treatment. The datas were analyzed statistically with independent t-test to find the differences of medication cost and day of treatment between c efotaxime an d chloramphenicol using. It resulted that the using of c efotaxime cost Rp. 1.075.000,00 and chloramphenicol took Rp. 714.200,00;day of treatment of c efotaxime using was 6 days and chloramphenicol was 4 days. The independent t- test showed that there were significant cost and LHR differences between c efotaxime and chloramphenicol using in medication of typhoid fever in children. The conclusion of this research is chloramphenicol has more cost-effective than c efotaxime in medication of typhoid fever in childrn.