Molar pregnancies

The gestational trophoblastic diseases are a spectrum of different clinical and pathological-defined affections. Treatment of complete and partial hydatidiform moles is dilatation-suction evacuation. It is necessary to control the evolution of hCG thereafter. In case of gestational trophoblastic neoplasia (GTN), defined on abnormal evolution of hCG or on a pathological diagnosis of choriocarcinoma, a medical treatment will be necessary. Choice of regimen will be done after different radiological exams, through a FIGO score assessment. In case of low risk GTN, methotrexate will be the usual treatment. High risk GTN will need polychemotherapy regimens. This article tries to give the essential points on diagnosis and treatment in gestational trophoblastic diseases, but also on more rare diseases such as placental site tumor or twin pregnancy with normal fetus and complete mole.