E-Cad、MMP9血清中的表达与胃癌痰湿证型关系的临床研究

Objective to observe the material base of phlegm in the tumor metastasis on the basis of the fact that similar biological features of tumor metastasis and pathological features of phlegm. Methods Enzyme-linked immunosorbent assay was adopted to detect E-Cad and MMP9 in 30 eases of gastric cancer of phlegm-dampness syndrome, 32 cases of gastric cancer of nun-phlegm-dampness syndrome and 10 healthy people. These 30 cases were treated with ”Xiaotan Sanjie Decoction” for one month. The contents of E-Cad and MMP9 were observed and compared. Results E-Cad and MMP9 were higher in patients with gastric cancer than in healthy people, in phlegm-dampness syndrome higher than in non-phlegm-dampness syndrome. Conclusion Phlegm may affect E-Cad and MMP9 in the tumor metastasis.