Partially Induced Hepatic Mixed-Function Oxidase Systems in Individual Members of Certain Marine Species from Coastal Maine and Florida

ABSTRACT Using elevated hepatic microsomal benzo(a)pyrene (AHH) hydroxylase activities and/or inhibition of AHH activity by a-naphtho-flavone (a-NF) in vitro as criteria for induction, 11 of 13 winter flounder (Pseudopleuronectes americanus) and 8 of 81 sheepshead (Archosargusprobatocephalus) tested had partially induced hepatic mixed-function oxidase systems. Such induction was not observed in any of the little skates (Rajaerinacea) or dogfish sharks (Squalusacanthias) studied.