Fibronectin splicing variants in human intervertebral disc and association with disc degeneration.

Study Design.In this study, normal intervertebral disc (IVD) tissues and degenerative human IVD tissues were compared for presence of fibronectin (FN) mRNA splice variants and for FN fragments (FN-f).Objective.To further understand FN RNA splice forms and protein fragments in disc degeneration.Summa