Preparing method of flupentixol compound

2013 
The present invention belongs to the field of medical technology, in particular to a thioxanthene compound fluoropiperidine, it 10- (3 dimethylaminopropylidene) -2-trifluoromethyl-thioxanthene (compound A) as a starting material or critical intermediate, which is reacted with the compound directly obtained hydroxyethylpiperazine flupentixol, which then fluoropiperidine hydrochloride salt formation to give the thioxanthone. This method is simple direct route, raw materials easily available, cheap, easy to save, simple operation, less side effects, low cost and easier to industrialize.
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