Antimalarial Principles from Artemisia indica

Activity-guided investigation of Artemisia indica Willd. has led to isolation of exiguaflavone A, exiguaflavone B, maackiain, and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran. Exiguaflavones A and B exhibit in vitro antimalarial activities of 4.60 × 10-6 and 7.05 × 10-6 g/mL, respectively, against Plasmodium falciparum.