Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

Tomas Vaisar,Jie Hong Hu,Nathan Airhart,Kate Fox,Jay W. Heinecke,Roberto F. Nicosia,Ted R. Kohler,Zachary E. Potter,Gabriel M. Simon,Melissa M. Dix,Benjamin F. Cravatt,Sina A. Gharib,David A. Dichek

Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

2020

Tomas Vaisar
Jie Hong Hu
Nathan Airhart
Kate Fox
Jay W. Heinecke
Roberto F. Nicosia
Ted R. Kohler
Zachary E. Potter
Gabriel M. Simon
Melissa M. Dix
Benjamin F. Cravatt
Sina A. Gharib
David A. Dichek

Rationale: Plaque rupture is the proximate cause of most myocardial infarctions and many strokes. However, the molecular mechanisms that precipitate plaque rupture are unknown. Objective: By applyi...

Keywords:

Basement membrane
Pathology
Internal medicine
Biology
Cardiology
Proteomics
plaque rupture

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