The rervising of biological exposure index for carbon disulfide exposuring

Objective To study the biological exposure index of carbon disulfide in china.Methods High-performance liquid chromatography (HPLC) was used to detect the levels of 2-thiothiazolidine-4-carboxylic acid (TTCA) in the urine of the workers after working shift end,Gas chromatography was used to detect the concentrations of the carbon disulfide in the workplace air.The relationship between the urine TTCA levels and the concentrations of the carbon disulfide was analyzed,the biological exposure index and judgement result from pC-TWA were compared.Results The levels of TTCA in urine of workers occupationally exposed to carbon disulfide were closely and positively related with the concentrations of the carbon disulfide in the workplace air.The regression equation was Y=0.265X-0.165,The biological exposure index of carbon disulfide were calculated by regression equation according to occupational exposure limits of carbon disulfide in China.Conclusion The biological exposure index of CS2 in China might be rersived for 1.2 mg/g Cr. Key words: Carbon disulfide; Occupational exposure; Biological exposure index