Detection of an IgM Antiglobulin in the Sera of Atopic Patients Using Insolubilised IgG4, and its Capacity to Release Histamine from Leucocytes

ELISA plates coated with highly pure IgG4 were employed to detect IgM antiglobulin in atopic sera. The use of IgG4, rather than whole IgG, on the solid-phase was to provide direct evidence for the IgG