Is There a Linking Cable between COVID-19 and Human Brain Diseases?

The novel Severe Acute Respiratory Syndrome (SARS-CoV-2) was first identified in Wuhan, China- 2019, which spreaded its extensions in whole world and made the world a sulking graveyard. There are seven different types of coronavirus, among which SARS-CoV has evolved itself in the nature and has become a life-threatening infection to mankind. This review is focused for the identification of linkage between the Novel Coronavirus(COVID-19) and human brain diseases. The common symptoms which are reported till now in COVID 19 are: fever, cough, fatigue, anosmia and ageusia. Whereas, the patients with more fatal infection are reported to suffer fromacute cerebrovascular diseases, impaired consciousness, skeletal muscle injury, arterial and venous thrombosis and acute necrotizing encephalopathy as severe symptoms. Its exact path for neural manifestation is still not established. However, it was expected to be attached with Angiotensin Converting Enzyme-2 (ACE-2), which interacts with capillary endothelium, thus breaking the Blood-Brain Barrier (BBB) and causing shortness of breath due to scarcity of oxygen. To confirm the exact source and path of neurological connection with COVID-19, there is need of autopsies which will give a light in this darkening situation of the world.