Granulomatous Liver Diseases

Hepatic granulomas develop through the interactions of T lymphocytes and macrophages. Granulomas are relatively common in liver samples, identified in 2–10% of cases. Granuloma formation is mainly due to infections, sarcoidosis, drug reactions, and primary biliary cholangitis. This article concisely reviews the classification, etiology, pathophysiology, clinical presentation, diagnosis, and treatment options of granulomatous liver diseases.