Effect of initial treatment protocol on prognosis of pneumonia in the kidney transplant recipients

Objective To explore the effects of different initial treatment protocols on the prognosis of pneumonia in the kidney transplant recipients. Methods Sixty-seven cases of pneumonia following kidney transplantation were divided into case group （34 cases） and control group （33 cases）.The patients in case group were treated with Imipenem and Cilastatin, SMX/TMP and ganciclovir,and those in control group received routine treatments. Mortality and length of stay in hospital （LOS）were analyzed. Results Mortality （5.9 % ） and LOS （15 days） in case group were reduced as compared with those in control group （ 18. 2 %, 23 days, respectively） （P〈 0. 05）. Among the patients without severe pneumonia, the mortality and incidence of LOS beyond 21 days in case group （3. 4 %, 1/29; 3. 4 %, 1/29） were lower than those in control group （17. 2 %, 5/29; 37. 9 %, 11/29, respectively） （P〈0. 05）. Whether the patients were admitted to hospital sooner or later, the incidence of LOS beyond 21 days in case group was lower than that in control group （P〈0. 05）.Whether the etiologies were determined or undetermined, the incidence of LOS beyond 21 days in case group was lower than that in control group （P〈0. 05）. The incidence of LOS beyond 21 days in case group was lower than that in control group among the patients with cardiopulmonary disease （P〈0. 05）. Conclusion The initial appropriate treatment would improve the prognosis of pneumonia in the kidney transplant recipients. Key words: Kidney transplantation;  Pneumonia;  Treatment protocols;  Prognosis