Imidazoline compound chirally synthesized by using thiourea catalyst derived from rosin and application thereof in anti-inflammatory and antipyretic aspects
2010
The invention discloses an imidazoline compound chirally synthesized by using a thiourea catalyst derived from rosin and application thereof in anti-inflammatory and antipyretic aspects. In the invention, a novel chiral thiourea catalyst A derived from rosin is synthesized in the whole synthesis process and can be used for successfully synthesizing the annular thiourea presented in the specification, accordingly, a type of novel imidazoline compound with the anti-inflammatory and antipyretic effects can be further chirally synthesized, and the novel imidazoline compound synthesized chirally is applied to the anti-inflammatory and antipyretic aspects.
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