P134 Health deprivation and post-COVID fibrosis: is there a relationship and what is the long-term impact?

P134 Table 1 10% most deprived Other Total 20 (43%) 26 (57%) Male sex 65% 54% Average age (years) 62.3 62.6 Maximal Fi02 < 0.6 13 (65%) 9 (35%) ITU admission 4 (20%) 10 (38%) T2DM 6 (30%) 3 (12%) Ex-smoker 13 (65%) 11 (42%) Average score fibrosis 10.06 10.14 ConclusionsWe have shown patients surviving COVID-19 who developed new fibrosis are significantly more likely to live within a deprived postcode. Patients within the 10% most deprived postcodes for health and disability are more likely to be male and ex-smokers. We also noted patients developing fibrotic changes on CT within lowest 10% for deprivation had lower rates of ITU admission and required lower FiO2 (indicating less severe disease) but with equivalent radiological findings to those within less deprived areas. Severe deprivation may in itself increase risk of developing long-term respiratory complications from COVID-19, propagating the ongoing cycle of health and deprivation.ReferencesMarmot M, et al. Build Back Fairer: The COVID-19 Marmot Review. The Pandemic, Socioeconomic and Health Inequalities in England. [Internet] London: Institute of Health Equity;2020. Available from https://www.health.org.uk/sites/default/files/upload/publications/2020/Build-back-fairer-the-COVID-19-Marmot-review.pdfHan X, et al. Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia. Radiology 2021 Jan 26;299(1):E177–E186.