Comparative study of same period and staging period of minimally invasive percutaneous nephrolithotomy surgery combined with flexible ureteroscopy lithotripsy treatment of complex renal calculi

Objective To investigate the efficacy and safety of single-channel percutaneous nephrolithotomy combined with flexible ureteroscopy lithotripsy in the treatment of complex renal stones. Methods Retrospective analysis of sixty cases of complex renal calculi diagnosed by radiology from January 2014 to July 2018. One-channel percutaneous nephrolithotomy combined with flexible ureteroscopy lithotripsy was performed in 30 patients during the same period and in stages. The stone clearance rate, length of hospital stays, and complications were compared between patients in the same period and in the staging group. Results Sixty patients with complex kidney stones underwent surgery successfully. The operative time in the same period group was shorter than that in the staging group [(161.9±19.2)min vs.(223.0±22.9)min, t=11.353, P=0.000]. The hospitalization period in the same period group was shorter than that in the staging group[(8.5±1.5) d vs.(14.5±1.8) d, t=14.152, P=0.000], the total cost of hospitalization in the same period was shorter than that of the staging group [(22186.9±1762.0) years vs.(33423.2±5464.5) years, t=11.058, P=0.000]. There was no statistical difference in stones between the same period group and the three-month period of the staging group [90.0%(27/30) vs.93.3%(28/30), Fisher's exact test, P=0.500]. There was no statistical difference in postoperative complications between the concomitant and staging groups[23.3%(7/30) vs.20.0%(6/30), χ2=0.098, P=0.754]. Conclusions Carrying out minimally invasive percutaneous nephrolithotomy surgery combined with flexible ureteroscopy lithotripsy treatment for patients with complex renal calculi is feasible and safe. Key words: Kidney Calculi; Nephrostomy, Percutaneous; Ureteroscopy; Lasers, Solid-State