Procedures for preparation of compounds of 4-amino-2- (2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione
2006
A process for preparing a compound of a process for preparing a compound of formula (I): or a salt, solvate, polimorformula (I): or a salt thereof, solvates, polymorphs or stereoisomers thereof aceptablesfos or stereoisomers thereof acceptable, comprising reacting etapade acid comprising the etapade reacting 3-aminophthalic acid or a salt thereof with compuesto3-aminophthalic or a salt thereof with a compound 3-5 aminoglutarimide of formula (X) or a 3-5 aminoglutarimide of formula (X) or a salt thereof: in a solvent and in the presence of tri its salts in a solvent and in the presence of triethylamine and acetic acid, wherein R1 is H, F, beetilamina and acetic acid, wherein R1 is H, F, benzyl, (C1-C8) alkyl, (C2-C8), or alquinilncilo, (C1-C8) alkyl, (C2-C8), or alkynyl (C2 C8). or (C2-C8).
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