Antifungal activity of Solanum melongena L, Lawsonia inermis L. and Justicia gendarussa B. against Dermatophytes.

2011 
Abstract: In vitro antifungal property of the chloroform, methanol and aqueous extracts of Solanum melongena L., Lawsonia inermis L. and Justicia gendarussa B. were evaluated against four common dermatophytic species, viz. Trichophyton mentagrophytes , Trichophyton rubrum , Microsporum gypseum and Microsporum fulvum adoptingAgar cup diffusion technique. Minimum inhibitory concentrations (MIC) for the extracts of the three plants wereestimated by the broth dilution method and values found ranging between 3.12 -12.5 mg/ml and above. The resultsdemonstrate the antidermatophytic nature of the selected plant extracts of which the chloroform extract of S.melongena was found to be the most potent. Key Words: Agar cup diffusion, Minimum inhibitory concentrations, Antidermatophytic. Introduction Dermatophytes are fungi capable of invadingkeratinized regions such as skin, hair, and nails ofhuman beings and animals, causing diseases known asdermatophytoses or dermatomycoses (1).Dermatomycoses due to
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