Systematic Review Snapshot TAKE-HOME MESSAGE When a patient with acute wrist pain is evaluated, the absence of snuffbox tenderness substantially decreases the probability of a scaphoid fracture. Alternatively, to definitively diagnose a scaphoid fracture, advanced imaging such as computed tomography (CT) or magnetic resonance imaging (MRI) may be necessary. What Physical Examination Findings and Diagnostic Imaging Modalities Are Most Useful in the Diagnosis of Scaphoid Fractures?