Distribution of coagulase-negative staphylococci from trauma patients and its drug resistance

OBJECTIVE To investigate the current status of infection caused by coagulase-negative staphylococcus(CNS) in trauma patients,and analyze the drug resistance.METHODS Staphylococcus isolated from the wound secretion of trauma patients from Jan 2005 to Dec 2009 were retrospectively analyzed.RESULTS Among 1068 strains of staphylococcus isolated from wound secretion,a total of 510 strains were CNS,accounting for 47.75%,among which,Staphylococcus epidermidis(377 strains) was on the first place,then was the Staphylococcus haemolyticus(120 strains) with an increased trend of the isolating rate year by year.Of the 510 CNS isolates,MSCNS(227 strains) and MRCNS(283 strains) were isolated with an increased trend of the isolating rate year by year.CNS appeared to be highly resistant to many commonly used antibiotics,especially to the commonly used three generations of cephalosporin and imipenem with a significantly.CNS was 100.00% susceptive to vancomycin and was with low resistance rate to netilmicin and minocycline.CONCLUSION It should pay more attention to the increased isolating rate and the multidrug resistance of CNS.Antibiotics should be used rationally according to the susceptibility test results.