Occlusion of the vas deferens in dogs with a biocompatible hydrogel solution

The surgically exposed vasa deferentia of 21 dogs were injected, under visual inspection, with Hypan N-90 acrylic hydrogel (50-150 μL). The hydrogel was deposited inside the vas lumen via a 22-gauge Teflon intercatheter. The solution gelled within 120 seconds. This highly biocompatible polymer solution, when gelled in contact with tissue fluid, offers safe and effective occlusion of the vas with the promise of reversibility