Multiple projection DEXA scanner for precision bone and muscle loss measurements and analysis during prolonged spaceflight

Bone structural information derived from DEXA data is shown to be relevant in explaining BMD loss versus strength-related observations in both aging populations and individuals exposed to microgravity for prolonged periods. Commercial DEXA instruments are limited (and not optimized) to make these critical structural measurements. Progress on the development of a multiple projection DEXA scanner system for making precision bone and muscle loss measurements and their resultant implications on bone strength and fracture risk is described.