The Clinical Characteristics and Risk Factors of Premature Coronary Artery Disease

Objective To investigate the correlation between the clinical characteristics of coronary lesions and risk factors of premature coronary heart disease(PCHD). Methods We retrospectively analyzed the data of 300 patients with coronary artery disease confirmed by coronary angiography. The patients were divided by age into PCHD group and late CHD(LCHD) group,with 150 patients in each group. The relationship among the risk factors including body mass index(BMI),history of hypertension,diabetes, hyperlipidemia,smoking, alcohol consumption,premature family history of cardiovascular disease,and level of lipidemia,and clinical features of coronary lesions in coronary features were analyzed. Results Patients with PCHD had higher levels of BMI, triglyceride(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-c) and LP(a) and lower incidence of diabetes than those in LCHD group(P0.05). Lesions in single branch of coronary artery were more common in patients with PCHD(P0.05).Conclusion Patients with PCHD have many clinical cardiovascular risk factors, including obesity, smoking, drinking, premature family history of cardiovascular disease, hyperlipemia,so early control of risk factors and early prevention can help reduce the incidence of PCHD.