Hematological, cytomorphological and histopathological diagnosis of transitional cell carcinoma in a male dog

An 8-year-old male German Shepherd dog with a history of hematuria, pollakiuria, stranguria and loss of appetite was tentatively diagnosed with urinary bladder neoplasia following hematology, urinalysis, cytology, normal abdominal radiographs and negative urine culture & sensitivity results. Abdominal ultrasound revealed a mass in the urinary bladder with considerable wall thickening and lowered treatment response to combination of chemotherapy and non-steroid anti-inflammatory drugs viz., vincristine and piroxicam respectively. The case confirmed to be a high grade transitional cell carcinoma by histopathology following euthanasia due to the poor prognosis.