Study on the antioxidation and lysozyme activities of Coelomactra antiquate.

Aim To study the antioxidation and lysozyme activities of Coelomactra antiquata. Methods The antioxidant activities of extract from Coelomactra antiquate were studied by measuring the effect of scavenging hyfroxyl free radical and activities of SOD,GSH-PX,LSZ. Results The results showed that the good scavenging effects of extract from Coelomactra antiquate were observed. The scavenging effects EC50 of liver and muscle were 1.29 mg·mL-1 and 4.41 mg·mL-1 respectively. When the extract concentration reached 0.5mg·mL-1,the effect in scavenging hydroxyl free radical of liver was 71.36±2.73U,an increase of 12.84% compared to that of at concentration of 0.1mg·mL -1 (63.24 ±1.85U). The effect in scavenging hydrroxyl free radical of muscle was 85.42±6.13U when concentration of the extract reached 4.0mg·mL-1,an increase of 2.31% compared with that at concentration of 0.5mg·mL-1 (64.56±8.12U). Conclusion The extract from Coelomactra antiquate could enhance antioxidative capacity significantly in vitro.