Combination of Acute Preoperative Plateletpheresis, Cell Salvage, and Aprotinin Minimizes Blood Loss and Requirement During Cardiac Surgery

Cardiovascular surgery with cardiopulmonary bypass (CPB) often is associated with the loss of large quantities of blood. Because massive blood loss and blood components transfusion are always associated with increased morbidity and mortality, and homologous blood products transfusion also exposes the patients to the risks of transfusion reaction and viral infection, it is critical to minimize the blood loss and transfusion requirement during cardiovascular surgery (1).