Effect of mitral valve surgery on severely impaired pulmonary function

: To evaluate the effect of surgery on severely impaired pulmonary function associated with mitral valve disease, we examined the relationship between postoperative improvements in pulmonary function and pulmonary circulation in 238 patients who underwent mitral valve surgery. Of these patients 17 met the preoperative criteria for severely impaired pulmonary function: forced expiratory volume in 1 second = FEV1 1000 ml. In long-surviving patients, pulmonary function improved in the late postoperative period. Significant relationships were recognized between delta FEV1 (delta: postoperative value--preoperative value) and delta PAP, delta PAWP, and delta PVR. The delta VC and delta %VC also correlated significantly with delta PAP, delta PAWP and delta PVR. In conclusion, in patients with mitral valve disease impaired pulmonary function cannot be used to exclude patients from operation. Furthermore, severely impaired pulmonary function should improve with the improvement of pulmonary circulation after surgery.