I2-Mediated Oxidative C—O Bond Formation for the Synthesis of 1,3,4-Oxadiazoles from Aldehydes and Hydrazides.

Wenquan Yu,Gang Huang,Yueteng Zhang,Hongxu Liu,Lihong Dong,Xuejun Yu,Yujiang Li,Junbiao Chang

I2-Mediated Oxidative C—O Bond Formation for the Synthesis of 1,3,4-Oxadiazoles from Aldehydes and Hydrazides.

2014

Wenquan Yu
Gang Huang
Yueteng Zhang
Hongxu Liu
Lihong Dong
Xuejun Yu
Yujiang Li
Junbiao Chang

Coupling of aldehydes and hydrazides followed by I2-mediated cyclization offers a simple, convenient, and environmentally friendly method to prepare symmetrically and asymmetrically substituted oxadiazoles.

Keywords:

Environmentally friendly
Oxidative phosphorylation
Chemistry
Organic chemistry
bond formation

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