Evaluation of yeast sludge cell wall and commercial clay based toxin binders against aflatoxin B1 on growth and serum parameters of broilers

A comparative study was conducted to evaluate yeast sludge cell wall (YSCW) and commercial toxin binders against different levels of aflatoxins B1 (AFB1) in broilers. A total of 390 one day old (1-d-o) chicks were divided into 13 groups with treatments (three replicates / treatment ten birds in each). Negative control (NC) contained no AFB1 and toxin binder in feed. Positive control (PC) was offered with different AFB1 levels (100, 200 and 300 µg/kg) in feed which were being produced in the laboratory earlier. The remaining treatments included YSCW, bentonites, combination of bentonites and glucomannan (Bent + Gluc) at different AFB1 levels in factorial arrangement from 8th to 28th days of age. Among positive control, 200 and 300 µg/kg AFB1 levels showed 37.42% and 36.38% decrease in weight gain causing 1.41 and 1.35 times increase in feed conversion ratio (FCR) compared to NC. YSCW and Bent + Gluc showed better weight gain (87.9, 83.45 and 75.48% for YSCW and 83.37, 82.83 and 78.35 for Bent + Gluc vs 66.26, 62.6 and 63.6% for PC as compared to NC) at 100, 200 and 300 µg AFB1/kg, respectively. The dietary treatments, aflatoxin levels and toxin binders showed non-significant effect for feed intake, serum alanine aminotransferase (ALAT) and significant on albumin and uric acid. It was concluded that AFB1 affect the growth at different levels significantly. Like other toxin binders, YSCW was found to nullify the deleterious effects of AFB1 and showed non-significant effect among themselves at different AFB1 levels.