Phase I dose escalation and PK study of thermally sensitive liposomes containing doxorubicin given during radiofrequency ablation (RFA) in patients with non-resectable primary and metastatic liver cancer

Brad Wood,Ronnie T.P. Poon,Ziv Neeman,Michelle Eugeni,J. Locklin,Sergio Dromi,S Kachala,R. Prabhakar,W Hahne,Steven K. Libutti

Phase I dose escalation and PK study of thermally sensitive liposomes containing doxorubicin given during radiofrequency ablation (RFA) in patients with non-resectable primary and metastatic liver cancer

2016

Brad Wood
Ronnie T.P. Poon
Ziv Neeman
Michelle Eugeni
J. Locklin
Sergio Dromi
S Kachala
R. Prabhakar
W Hahne
Steven K. Libutti

15010 Purpose: This phase I dose escalation and pharmacokinetic (PK) study in patients with non-resectable primary or metastatic hepatic tumors undergoing radiofrequency ablation (RFA) uses a 30-mi...

Keywords:

Metastatic liver cancer
Radiofrequency ablation
Urology
Pathology
Doxorubicin
Liposome
Pharmacokinetics
Medicine
dose escalation
in patient

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