p53-cyclophilin D mediates renal tubular cell apoptosis in ischemia-reperfusion-induced acute kidney injury

Huan Yang,Ruizhao Li,Li Zhang,Shu Zhang,Wei Dong,Yuanhan Chen,Weidong Wang,Chunling Li,Zhiming Ye,Xingchen Zhao,Zhilian Li,Yanhua Wu,Mengxi Zhang,Shuangxin Liu,Zheng Dong,Xinling Liang

p53-cyclophilin D mediates renal tubular cell apoptosis in ischemia-reperfusion-induced acute kidney injury

2019

Huan Yang
Ruizhao Li
Li Zhang
Shu Zhang
Wei Dong
Yuanhan Chen
Weidong Wang
Chunling Li
Zhiming Ye
Xingchen Zhao
Zhilian Li
Yanhua Wu
Mengxi Zhang
Shuangxin Liu
Zheng Dong
Xinling Liang

Ischemia-reperfusion-induced acute kidney injury (IR-AKI) favors mitochondrial permeability transition pore (mPTP) opening and subsequent cell death. Cyclophilin D (CypD) is an essential component ...

Keywords:

Mitochondrial permeability transition pore
Diabetes mellitus
Ischemia
Cyclophilin D
Biochemistry
Biology
Apoptosis
Acute kidney injury
Programmed cell death
Pharmacology
MPTP

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