A novel Germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men

Xiaoling Lin,Lianxi Qu,Zhuo Chen,Chuanliang Xu,Dingwei Ye,Qiang Shao,Xiang Wang,Jun Qi,Zhiwen Chen,Fangjian Zhou,Meilin Wang,Zhong Wang,Dalin He,Denglong Wu,Xin Gao,Jianlin Yuan,G. Wang,Yong Xu,Guozeng Wang,Pei Dong,Yang Jiao,Jin Yang,Jun OuYang,Haowen Jiang,Yao Zhu,Shancheng Ren,Zhengdong Zhang,Changjun Yin,Qijun Wu,Ying Zheng,Aubrey R. Turner,Sha Tao,Rong Na,Qiang Ding,Daru Lu,Rong Shi,Jielin Sun,Fang Liu,S. Lilly Zheng,Zengnan Mo,Yinghao Sun,Jianfeng Xu

A novel Germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men

2013

BACKGROUND A rare mutation G84E in HOXB13 was recently identified to be associated with prostate cancer (PCa) in Caucasians. The goal of this study is to test association between HOXB13 genetic variants and PCa risk in Chinese men.

Keywords:

Cancer research
Endocrinology
Prostate cancer
Prostate cancer risk
Germline mutation
Mutation
Internal medicine
Biology
genetic variants
chinese men
amino acid substitution

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