Homozygous mutation of the IGF1 receptor gene in a patient with severe pre- and postnatal growth failure and congenital malformations

Homozygous mutation of the IGF1 receptor gene in a patient with severe preand postnatal growth failure and congenital malformations Marie-Helene Gannage-Yared*, Jurgen Klammt*, Eliane Chouery, Sandra Corbani, Hala Megarbane, Joelle Abou Ghoch, Nancy Choucair, Roland Pfaffle and Andre Megarbane Service d’Endocrinologie, Hotel-Dieu de France Hospital, Beirut, Lebanon, Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany, Unite de Genetique Medicale et Laboratoire Associe INSERM UMR_S910, Faculte de Medecine, Pole Technologie Sante, Universite Saint-Joseph, Beirut, Lebanon, Department of Dermatology, Saint Georges Hospital, University of Balamand, Beirut, Lebanon and Institut Jerome Lejeune, Paris, France