Pre-clinical Testing of the Polymer Implants Enriched of Ceramic Materials with aim on Rate of Osteointegration in a Rabbit Model

The purpose of this paper was writing down the process of preclinical testing which consisted from usage of bioinert polymer material enriched with bioactive ceramic elements. The testing was preceded by a study of the current state and methods of implantation of polymer implants. The created samples were implanted into the animal subject femoral bone with purpose to observe the rate of osteointegration process for twelve weeks. Subsequently were the bones dissected, stripped of soft tissue and observed under stereomicroscope and submitted to histological evaluation. The whole process was detailly recorded and it is prepared for further clinical studies in field of implantation of biocompatible polymer materia